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Pharmacy Expertwitess & Consultant
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Pharmacology may be the basis of Causation
Pharmacology is the study of how substances affect a living organisms.
How does the substance change the normal function. (Nagle 2005 ).
Clinical Pharmacology
Medication effects specifically in humans
Example of Pharmacology or Pharmacodynamics - Ethyl Alcohol
Alcohol is a drug that produce a depressant effect and agitation. The depressant effect is considerably short effect than the depressant effect.
Alcohol is though to disturb the synaptic activity of various neurotransmitters. It may also disturb various intracellular transduction pathways.
Glutamate Receptors
Alcohol is an inhibitor of the function of the glutamate receptor. It depresses the responsiveness of NMDA receptors to release glutamate. With continued alcohol use, the NMDA receptors become more active. When the alcohol is suddenly stopped, this increased activity in the receptors can lead to tremors and seizures.
GABA Receptors
Alcohol triggers a response from GABA induced chloride ion flow which causes neuronal stopping.
This causes sedation, muscle relaxation, and cognitive/motor skill decreases.
My Experience
I have worked with attorneys in developing their case. First, to show how a drug works in the body and its' effect at a cellular level. Then providing a pharmacologic explanation that the drug was the cause of the clients adverse experience.
| Civil Defense/Plaintiff | Criminal Pharmacy Matters | Pharmaceutical Industry |
| Wrongful Death Claims | HOME | FDA Marketing Reg. |
| Certificate of Merit | Insurance Fraud | Pharmacoeconomics |
| Professional Board Infractions | Drug Overdose | cGood Manufacturing Practices |
| Retail Pharmacy | Drug Addiction | Drug Products Liability |
| Pharmacy Standard of Care | Narcotic Inventory Audit | Pharmaceutical Promotion |
| Pharmacy Wholesaler Importation | ePrescribing | |
| Hospital/Clinical Pharmacy | Pharmacokinetics | Promotional Campaign Review |